High glucose induces formation of tau hyperphosphorylation via Cav-1-mTOR pathway: A potential molecular mechanism for diabetes-induced cognitive dysfunction

The abnormally hyperphosphorylated tau is thought to be implicated in diabetes-associated cognitive deficits. The role of mammalian target of rapamycin (mTOR) / S6 kinase (S6K) signalling in the formation of tau hyperphosphorylation has been previously studied. Caveolin-1 (Cav-1), the essential stru...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Jing, Zhou, Shan-Lei, Pi, Lin-Hua, Shi, Xia-Jie, Ma, Ling-Ran, Chen, Zi, Qu, Min-Li, Li, Xin, Nie, Sheng-Dan, Liao, Duan-Fang, Pei, Jin-Jing, Wang, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522306/
https://ncbi.nlm.nih.gov/pubmed/28489581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17257
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados