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The autophagic degradation of Cav-1 contributes to PA-induced apoptosis and inflammation of astrocytes
The accumulation of palmitic acid (PA), implicated in obesity, can induce apoptotic cell death and inflammation of astrocytes. Caveolin-1 (Cav-1), an essential protein for astrocytes survival, can be degraded by autophagy, which is a double-edge sword that can either promote cell survival or cell de...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039485/ https://ncbi.nlm.nih.gov/pubmed/29991726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0795-3 |
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