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Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth

Delta-like 4 (DLL4) and Jagged1 (JAG1) are two key Notch ligands implicated in tumour angiogenesis. They were shown to have opposite effects on mouse retinal and adult regenerative angiogenesis. In tumours, both ligands are upregulated but their relative effects and interactions in tumour biology, p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Oon, Chern Ein, Bridges, Esther, Sheldon, Helen, Sainson, Richard C.A., Jubb, Adrian, Turley, Helen, Leek, Russell, Buffa, Francesca, Harris, Adrian L., Li, Ji-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522274/
https://ncbi.nlm.nih.gov/pubmed/28445154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16969
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