The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia and is a key mediator of estrogen induced growth

ERα plays an important role in breast cancer. Up-regulation of HIF-1α in ERα-positive cancers suggests that HIF-1α may cooperate with ERα to promote breast cancer progression and consequently affect breast cancer treatment. Here we show the histone demethylase JMJD2B is regulated by both ERα and HIF...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Yang, Jun, Jubb, Adrian M., Pike, Luke, Buffa, Francesca M., Turley, Helen, Baban, Dilair, Leek, Russell, Gatter, Kevin C., Ragoussis, Jiannis, Harris, Adrian L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261152/
https://ncbi.nlm.nih.gov/pubmed/20682797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0413
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