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The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia and is a key mediator of estrogen induced growth
ERα plays an important role in breast cancer. Up-regulation of HIF-1α in ERα-positive cancers suggests that HIF-1α may cooperate with ERα to promote breast cancer progression and consequently affect breast cancer treatment. Here we show the histone demethylase JMJD2B is regulated by both ERα and HIF...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cancer Res |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261152/ https://ncbi.nlm.nih.gov/pubmed/20682797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0413 |
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