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An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells

Acute myeloid leukemia (AML) is characterized by an aggressive clinical course and frequent cytogenetic abnormalities that include specific chromosomal translocations. The 8;21 chromosomal rearrangement disrupts the key hematopoietic RUNX1 transcription factor, and contributes to leukemia through re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zaidi, Sayyed K., Perez, Andrew W., White, Elizabeth S., Lian, Jane B., Stein, Janet L., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522207/
https://ncbi.nlm.nih.gov/pubmed/28611288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18127
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