An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells

Acute myeloid leukemia (AML) is characterized by an aggressive clinical course and frequent cytogenetic abnormalities that include specific chromosomal translocations. The 8;21 chromosomal rearrangement disrupts the key hematopoietic RUNX1 transcription factor, and contributes to leukemia through re...

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Vydáno v:Oncotarget
Hlavní autoři: Zaidi, Sayyed K., Perez, Andrew W., White, Elizabeth S., Lian, Jane B., Stein, Janet L., Stein, Gary S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522207/
https://ncbi.nlm.nih.gov/pubmed/28611288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18127
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