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An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells

Acute myeloid leukemia (AML) is characterized by an aggressive clinical course and frequent cytogenetic abnormalities that include specific chromosomal translocations. The 8;21 chromosomal rearrangement disrupts the key hematopoietic RUNX1 transcription factor, and contributes to leukemia through re...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Zaidi, Sayyed K., Perez, Andrew W., White, Elizabeth S., Lian, Jane B., Stein, Janet L., Stein, Gary S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522207/
https://ncbi.nlm.nih.gov/pubmed/28611288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18127
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