Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery

Bcl-2 gene is an important target to treat lung cancer. The small interference RNA (siRNA) of Bcl-2 gene (siBcl-2) can specifically silence Bcl-2 gene. However, naked siBcl-2 is difficult to accumulate in the tumor tissue to exert its activity. In this paper, a calcium phosphate lipid hybrid nanopar...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Cai, Rong-Qiao, Liu, Dao-Zhou, Cui, Han, Cheng, Ying, Liu, Miao, Zhang, Bang-Le, Mei, Qi-Bing, Zhou, Si-Yuan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522105/
https://ncbi.nlm.nih.gov/pubmed/28514759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17484
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