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Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition
Modulation of the immune system for the treatment of primary and metastatic tumors has been a goal of cancer research for many years. The E3 ubiquitin ligase Cbl-b has been established as an intracellular checkpoint that limits T cell activation, critically contributing to the maintenance of self-to...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522032/ https://ncbi.nlm.nih.gov/pubmed/28611299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18360 |
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