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Delineation of antigen contact residues on an MHC class II molecule.

This report describes a detailed mutational analysis of a major histocompatibility complex class II molecule--the alpha chain of the Ak complex. Each residue from 50-79 was replaced by an alanine, and the effects on recognition of Ak by panels of antibodies and T cells determined. The results provid...

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Autori principali: Peccoud, J, Dellabona, P, Allen, P, Benoist, C, Mathis, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC552203/
https://ncbi.nlm.nih.gov/pubmed/2265605
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