Specific structural alteration of the influenza haemagglutinin by amantadine.

Amantadine hydrochloride specifically blocks the release of virus particles from H7 influenza virus infected cells. This appears to be the direct consequence of an amantadine induced change in the haemagglutinin (HA) to its low pH conformation. The effect is indirect and mediated via interaction of...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Sugrue, R J, Bahadur, G, Zambon, M C, Hall-Smith, M, Douglas, A R, Hay, A J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2209554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07555.x
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