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Reversion of a transcriptionally defective MHC class II-negative human B-cell mutant.

RJ2.2.5, a mutant derived from the human B-lymphoma cell, Raji, is unable to express the MHC class II genes because of a recessive transcriptional defect attributed to the lack of an activator function. We report the isolation of a RJ2.2.5 revertant, namely AR, in which the expression of the mRNAs e...

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Библиографические подробности
Главные авторы: Ombra, M N, Perfetto, C, Autiero, M, Anzisi, A M, Pasquinelli, R, Maffei, A, Del Pozzo, G, Guardiola, J
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC309128/
https://ncbi.nlm.nih.gov/pubmed/8441650
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