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Direct targets of pSTAT5 signalling in erythropoiesis

Erythropoietin (EPO) acts through the dimeric erythropoietin receptor to stimulate proliferation, survival, differentiation and enucleation of erythroid progenitor cells. We undertook two complimentary approaches to find EPO-dependent pSTAT5 target genes in murine erythroid cells: RNA-seq of newly t...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Gillinder, Kevin R., Tuckey, Hugh, Bell, Charles C., Magor, Graham W., Huang, Stephen, Ilsley, Melissa D., Perkins, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521770/
https://ncbi.nlm.nih.gov/pubmed/28732065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180922
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