Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

RU486 induced the binding to a palindromic progestin responsive element (PRE) in vitro of homo- and heterodimers of the human progesterone receptor (hPR) isoforms A and B, present in T47D breast cancer cells or in HeLa cells transiently expressing the recombinant proteins. The resulting complexes we...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Meyer, M E, Pornon, A, Ji, J W, Bocquel, M T, Chambon, P, Gronemeyer, H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2249658/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07613.x
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