Molecular mechanisms in down-regulation of tumor necrosis factor expression.

Excessive production of tumor necrosis factor (TNF) after stimulation by lipopolysaccharide (LPS) may result in fever, intravascular coagulation, and lethal shock. An efficient way of preventing the excessive TNF production is desensitization of monocytes/macrophages to LPS. We have analyzed the mol...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Haas, J G, Baeuerle, P A, Riethmüller, G, Ziegler-Heitbrock, H W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9563
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