Molecular mechanisms in down-regulation of tumor necrosis factor expression.

Excessive production of tumor necrosis factor (TNF) after stimulation by lipopolysaccharide (LPS) may result in fever, intravascular coagulation, and lethal shock. An efficient way of preventing the excessive TNF production is desensitization of monocytes/macrophages to LPS. We have analyzed the mol...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Haas, J G, Baeuerle, P A, Riethmüller, G, Ziegler-Heitbrock, H W
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9563
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