Molecular mechanisms in down-regulation of tumor necrosis factor expression.

Excessive production of tumor necrosis factor (TNF) after stimulation by lipopolysaccharide (LPS) may result in fever, intravascular coagulation, and lethal shock. An efficient way of preventing the excessive TNF production is desensitization of monocytes/macrophages to LPS. We have analyzed the mol...

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Autors principals: Haas, J G, Baeuerle, P A, Riethmüller, G, Ziegler-Heitbrock, H W
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55212/
https://ncbi.nlm.nih.gov/pubmed/2263611
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