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Molecular mechanisms in down-regulation of tumor necrosis factor expression.

Excessive production of tumor necrosis factor (TNF) after stimulation by lipopolysaccharide (LPS) may result in fever, intravascular coagulation, and lethal shock. An efficient way of preventing the excessive TNF production is desensitization of monocytes/macrophages to LPS. We have analyzed the mol...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Haas, J G, Baeuerle, P A, Riethmüller, G, Ziegler-Heitbrock, H W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55212/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9563
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