Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system

Melanocytic tumors originating in the central nervous system (MT-CNS) are rare tumors that generally have a favorable prognosis, however malignant tumors do occur. Pathogenetically MT-CNS are not well characterized. Similar to uveal melanoma and blue nevi, they frequently harbor activating GNAQ or G...

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Udgivet i:J Neurooncol
Main Authors: van de Nes, Johannes, Gessi, Marco, Sucker, Antje, Moller, Inga, Stiller, Mathias, Horn, Susanne, Scholz, Simone L., Pischler, Carina, Stadtler, Nadine, Schilling, Bastian, Zimmer, Lisa, Hillen, Uwe, Scolyer, Richard A., Buckland, Michael E., Lauriola, Libero, Pietsch, Torsten, Waha, Andreas, Schadendorf, Dirk, Murali, Rajmohan, Griewank, Klaus G.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521190/
https://ncbi.nlm.nih.gov/pubmed/26744134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-2052-2
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