טוען...
A gradient of sitewise diversity promotes evolutionary fitness for binder discovery in a three-helix bundle protein scaffold
Engineered proteins provide clinically and industrially impactful molecules and utility within fundamental research. Yet, inefficiencies in discovering lead variants with new desired function, while maintaining stability, hinder progress. Improved function, which can result from a few strategic muta...
שמור ב:
| הוצא לאור ב: | Biochemistry |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521020/ https://ncbi.nlm.nih.gov/pubmed/28248518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01142 |
| תגים: |
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