The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo

Cyanidin, a key flavonoid that is present in red berries and other fruits, attenuates the development of several diseases, including asthma, diabetes, atherosclerosis, and cancer, through its anti-inflammatory effects. We investigated the molecular basis of cyanidin action. Through a structure-based...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Liu, Caini, Zhu, Liang, Fukuda, Koichi, Ouyang, Suidong, Chen, Xing, Wang, Chenhui, Zhang, Cun-jin, Martin, Bradley, Gu, Chunfang, Qin, Luke, Rachakonda, Suguna, Aronica, Mark, Qin, Jun, Li, Xiaoxia
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520994/
https://ncbi.nlm.nih.gov/pubmed/28223414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf8823
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