Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons

Autophagy is triggered during nutrient and energy deprivation in a variety of cells as a homeostatic response to metabolic stress. In the CNS, deficient autophagy has been implicated in neurodegenerative diseases and ischemic brain injury. However, its role in hypoglycemic damage is poorly understoo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Gerónimo-Olvera, Cristian, Montiel, Teresa, Rincon-Heredia, Ruth, Castro-Obregón, Susana, Massieu, Lourdes
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520945/
https://ncbi.nlm.nih.gov/pubmed/28661473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.299
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