Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy

Senescent cells accumulate in various tissues and organs with aging altering surrounding tissue due to an active secretome, and at least in mice their elimination extends healthy lifespan and ameliorates several chronic diseases. Whether all cell types senesce, including post-mitotic cells, has been...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Moreno-Blas, Daniel, Gorostieta-Salas, Elisa, Pommer-Alba, Alexander, Muciño-Hernández, Gabriel, Gerónimo-Olvera, Cristian, Maciel-Barón, Luis Angel, Konigsberg, Mina, Massieu, Lourdes, Castro-Obregón, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738425/
https://ncbi.nlm.nih.gov/pubmed/31469660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102181
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