Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition

Histone deacetylase 3 (HDAC3) has an oncogenic role in apoptosis and contributes to the proliferation of cancer cells. MI192 is a novel HDAC3-specific inhibitor that displays antitumor activity in many cancer cell lines. However, the role of HDAC3 and the antitumor activity of its inhibitor MI192 ar...

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Vydáno v:Cell Death Dis
Hlavní autoři: Yin, Yuyao, Zhang, Mingming, Dorfman, Robert Gregory, Li, Yang, Zhao, Zhenguo, Pan, Yida, Zhou, Qian, Huang, Shan, Zhao, Shimin, Yao, Yuling, Zou, Xiaoping
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520875/
https://ncbi.nlm.nih.gov/pubmed/28569784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.457
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