Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons

Tau is a microtubule-associated protein exerting several physiological functions in neurons. In Alzheimer's disease (AD) misfolded tau accumulates intraneuronally and leads to axonal degeneration. However, tau has also been found in the extracellular medium. Recent studies indicated that extrac...

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Bibliografiska uppgifter
I publikationen:Glia
Huvudupphovsmän: Piacentini, Roberto, Puma, Domenica Donatella Li, Mainardi, Marco, Lazzarino, Giacomo, Tavazzi, Barbara, Arancio, Ottavio, Grassi, Claudio
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520670/
https://ncbi.nlm.nih.gov/pubmed/28519902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23163
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https://ncbi.nlm.nih.gov/pmc/articles/PMC5520670/
https://ncbi.nlm.nih.gov/pubmed/28519902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23163

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