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Pharmacogenomic Markers of Targeted Therapy Toxicity in Patients with Metastatic Renal Cell Carcinoma

BACKGROUND: Targeted therapy (TT) in metastatic renal cell carcinoma (mRCC) may be associated with a high rate of toxicity that undermines treatment efficacy and patient quality of life. Polymorphisms in genes involved in the pharmacokinetic pathways of TTs may predict toxicity. OBJECTIVE: To invest...

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Detalhes bibliográficos
Publicado no:Eur Urol Focus
Main Authors: de Velasco, Guillermo, Gray, Kathryn P., Hamieh, Lana, Urun, Yuksel, Carol, Hallie A., Fay, Andre P., Signoretti, Sabina, Kwiatkowski, David J., McDermott, David F., Freedman, Matthew, Pomerantz, Mark M., Choueiri, Toni K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520643/
https://ncbi.nlm.nih.gov/pubmed/28723497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euf.2016.03.017
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