Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia

BACKGROUND: In B-cell precursor acute lymphoblastic leukaemia (B-ALL), the identification of additional genetic alterations associated with poor prognosis is still of importance. We determined the frequency and prognostic impact of somatic mutations in children and adult cases with B-ALL treated wit...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Forero-Castro, Maribel, Robledo, Cristina, Benito, Rocío, Bodega-Mayor, Irene, Rapado, Inmaculada, Hernández-Sánchez, María, Abáigar, María, Maria Hernández-Sánchez, Jesús, Quijada-Álamo, Miguel, María Sánchez-Pina, José, Sala-Valdés, Mónica, Araujo-Silva, Fernanda, Kohlmann, Alexander, Luis Fuster, José, Arefi, Maryam, de las Heras, Natalia, Riesco, Susana, Rodríguez, Juan N, Hermosín, Lourdes, Ribera, Jordi, Camos Guijosa, Mireia, Ramírez, Manuel, de Heredia Rubio, Cristina Díaz, Barragán, Eva, Martínez, Joaquín, Ribera, José M, Fernández-Ruiz, Elena, Hernández-Rivas, Jesús-María
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520505/
https://ncbi.nlm.nih.gov/pubmed/28557976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.152
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