RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice

RIP1 is an essential regulator of TNF-induced signaling complexes mediating NF-κB activation, apoptosis and necroptosis. Loss of Rip1 rescues the embryonic lethality of Fadd or Caspase-8-deficient mice, even though the double knockout mice die shortly after birth like Rip1-deficient mice. Recent stu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Differ
Autori principali: Liu, Yongbo, Fan, Cunxian, Zhang, Yifan, Yu, Xianjun, Wu, Xiaoxia, Zhang, Xixi, Zhao, Qun, Zhang, Haiwei, Xie, Qun, Li, Ming, Li, Xiaoming, Ding, Qiurong, Ying, Hao, Li, Dali, Zhang, Haibing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
Soggetti:
Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520462/
https://ncbi.nlm.nih.gov/pubmed/28574501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.78
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi