RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice

RIP1 is an essential regulator of TNF-induced signaling complexes mediating NF-κB activation, apoptosis and necroptosis. Loss of Rip1 rescues the embryonic lethality of Fadd or Caspase-8-deficient mice, even though the double knockout mice die shortly after birth like Rip1-deficient mice. Recent stu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Death Differ
Hlavní autoři: Liu, Yongbo, Fan, Cunxian, Zhang, Yifan, Yu, Xianjun, Wu, Xiaoxia, Zhang, Xixi, Zhao, Qun, Zhang, Haiwei, Xie, Qun, Li, Ming, Li, Xiaoming, Ding, Qiurong, Ying, Hao, Li, Dali, Zhang, Haibing
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520462/
https://ncbi.nlm.nih.gov/pubmed/28574501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.78
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky