Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease

Classical Whipple's disease (CWD) is characterized by the lack of specific Th1 response toward Tropheryma whipplei in genetically predisposed individuals. The cofactor GrpE of heat shock protein 70 (Hsp70) from T. whipplei was previously identified as a B-cell antigen. We tested the capacity of...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Trotta, Lucia, Weigt, Kathleen, Schinnerling, Katina, Geelhaar-Karsch, Anika, Oelkers, Gerrit, Biagi, Federico, Corazza, Gino Roberto, Allers, Kristina, Schneider, Thomas, Erben, Ulrike, Moos, Verena
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Host Response and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520441/
https://ncbi.nlm.nih.gov/pubmed/28559404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00363-17
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