Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease

Classical Whipple's disease (CWD) is characterized by the lack of specific Th1 response toward Tropheryma whipplei in genetically predisposed individuals. The cofactor GrpE of heat shock protein 70 (Hsp70) from T. whipplei was previously identified as a B-cell antigen. We tested the capacity of...

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Xehetasun bibliografikoak
Argitaratua izan da:Infect Immun
Egile Nagusiak: Trotta, Lucia, Weigt, Kathleen, Schinnerling, Katina, Geelhaar-Karsch, Anika, Oelkers, Gerrit, Biagi, Federico, Corazza, Gino Roberto, Allers, Kristina, Schneider, Thomas, Erben, Ulrike, Moos, Verena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Host Response and Inflammation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520441/
https://ncbi.nlm.nih.gov/pubmed/28559404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00363-17
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