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Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease

Classical Whipple's disease (CWD) is characterized by the lack of specific Th1 response toward Tropheryma whipplei in genetically predisposed individuals. The cofactor GrpE of heat shock protein 70 (Hsp70) from T. whipplei was previously identified as a B-cell antigen. We tested the capacity of...

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Foilsithe in:Infect Immun
Main Authors: Trotta, Lucia, Weigt, Kathleen, Schinnerling, Katina, Geelhaar-Karsch, Anika, Oelkers, Gerrit, Biagi, Federico, Corazza, Gino Roberto, Allers, Kristina, Schneider, Thomas, Erben, Ulrike, Moos, Verena
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520441/
https://ncbi.nlm.nih.gov/pubmed/28559404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00363-17
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