Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier

To achieve synergistic therapeutic efficacy and prevent cancer relapse, chemotherapy and immunotherapy have been combined as a new modality for tumor treatment. In this work, we designed a redox-responsive immunostimulatory polymeric prodrug carrier, PSSN10, for programmable co-delivery of an immune...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Sun, Jing-jing, Chen, Yi-chao, Huang, Yi-xian, Zhao, Wen-chen, Liu, Yan-hua, Venkataramanan, Raman, Lu, Bin-feng, Li, Song
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520195/
https://ncbi.nlm.nih.gov/pubmed/28504251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.44
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