Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death

Activating alternative cell death pathways, including autophagic cell death, is a promising direction to overcome the apoptosis resistance observed in various cancers. Yet, whether autophagy acts as a death mechanism by over consumption of intracellular components is still controversial and remains...

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Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: Dasari, Santosh K, Bialik, Shani, Levin-Zaidman, Smadar, Levin-Salomon, Vered, Merrill, Alfred H, Futerman, Anthony H, Kimchi, Adi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520177/
https://ncbi.nlm.nih.gov/pubmed/28574511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.80
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