Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death

Activating alternative cell death pathways, including autophagic cell death, is a promising direction to overcome the apoptosis resistance observed in various cancers. Yet, whether autophagy acts as a death mechanism by over consumption of intracellular components is still controversial and remains...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Death Differ
Главные авторы: Dasari, Santosh K, Bialik, Shani, Levin-Zaidman, Smadar, Levin-Salomon, Vered, Merrill, Alfred H, Futerman, Anthony H, Kimchi, Adi
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
Предметы:
Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520177/
https://ncbi.nlm.nih.gov/pubmed/28574511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.80
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы