Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair

HBO1, a histone acetyl transferase, is a co-activator of DNA pre-replication complex formation. We recently reported that HBO1 is phosphorylated by ATM and/or ATR and binds to DDB2 after ultraviolet irradiation. Here, we show that phosphorylated HBO1 at cyclobutane pyrimidine dimer (CPD) sites media...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Niida, Hiroyuki, Matsunuma, Ryoichi, Horiguchi, Ryo, Uchida, Chiharu, Nakazawa, Yuka, Motegi, Akira, Nishimoto, Koji, Sakai, Satoshi, Ohhata, Tatsuya, Kitagawa, Kyoko, Moriwaki, Shinichi, Nishitani, Hideo, Ui, Ayako, Ogi, Tomoo, Kitagawa, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520108/
https://ncbi.nlm.nih.gov/pubmed/28719581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16102
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