UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4(DDB2)-Mediated Degradation To Regulate Cell Proliferation

Histone acetyltransferase binding to ORC-1 (HBO1) is a critically important histone acetyltransferase for forming the prereplicative complex (pre-RC) at the replication origin. Pre-RC formation is completed by loading of the MCM2-7 heterohexameric complex, which functions as a helicase in DNA replic...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Matsunuma, Ryoichi, Niida, Hiroyuki, Ohhata, Tatsuya, Kitagawa, Kyoko, Sakai, Satoshi, Uchida, Chiharu, Shiotani, Bunsyo, Matsumoto, Masaki, Nakayama, Keiichi I., Ogura, Hiroyuki, Shiiya, Norihiko, Kitagawa, Masatoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719422/
https://ncbi.nlm.nih.gov/pubmed/26572825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00809-15
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