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Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity
BACKGROUND: We investigated the predictive value of dihydropyrimidine dehydrogenase (DPD) phenotype, measured as pretreatment serum uracil and dihydrouracil concentrations, for severe as well as fatal fluoropyrimidine-associated toxicity in 550 patients treated previously with fluoropyrimidines duri...
שמור ב:
| הוצא לאור ב: | Br J Cancer |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520099/ https://ncbi.nlm.nih.gov/pubmed/28427087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.94 |
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