Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution

The cellular ESCRT-III (endosomal sorting complex required for transport-III) and Vps4 (vacuolar protein sorting 4) comprise a common machinery that mediates a variety of membrane remodelling events. Vps4 is essential for the machinery function by using the energy from ATP hydrolysis to disassemble...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Sun, Shan, Li, Lin, Yang, Fan, Wang, Xiaojing, Fan, Fenghui, Yang, Mengyi, Chen, Chunlai, Li, Xueming, Wang, Hong-Wei, Sui, Sen-Fang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520056/
https://ncbi.nlm.nih.gov/pubmed/28714467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16064
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