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Endolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines

A major problem with many promising nano-sized biotherapeutics including macromolecules is that owing to their size they are subject to cellular uptake via endocytosis, and become entrapped and then degraded within endolysosomes, which can significantly impair their therapeutic efficacy. Photochemic...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Yaghini, Elnaz, Dondi, Ruggero, Tewari, Kunal M., Loizidou, Marilena, Eggleston, Ian M., MacRobert, Alexander J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519633/
https://ncbi.nlm.nih.gov/pubmed/28729656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06109-y
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