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Endolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines
A major problem with many promising nano-sized biotherapeutics including macromolecules is that owing to their size they are subject to cellular uptake via endocytosis, and become entrapped and then degraded within endolysosomes, which can significantly impair their therapeutic efficacy. Photochemic...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519633/ https://ncbi.nlm.nih.gov/pubmed/28729656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06109-y |
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