RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia

Transcripts for α9 and α10 nicotinic acetylcholine receptor (nAChR) subunits are found in diverse tissues. The function of α9α10 nAChRs is best known in mechanosensory cochlear hair cells, but elsewhere their roles are less well-understood. α9α10 nAChRs have been implicated as analgesic targets and...

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Udgivet i:Front Cell Neurosci
Main Authors: Christensen, Sean B., Hone, Arik J., Roux, Isabelle, Kniazeff, Julie, Pin, Jean-Philippe, Upert, Grégory, Servent, Denis, Glowatzki, Elisabeth, McIntosh, J. Michael
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519620/
https://ncbi.nlm.nih.gov/pubmed/28785206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00219
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