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Cell Biology and Pathophysiology of α-Synuclein

α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve terminals. Genetics and neuropathology studies link α-synuclein to Parkinson’s disease (PD) and other neurodegenerative disorders. Accumulation of misfolded oligomers and larger aggregates of α-synuclein defines...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Perspect Med
Main Authors: Burré, Jacqueline, Sharma, Manu, Südhof, Thomas C.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519445/
https://ncbi.nlm.nih.gov/pubmed/28108534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024091
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