miR181b-3p and its target importin α5 regulate TLR4 signaling in Kupffer cells and liver injury in mice in response to ethanol

Increased inflammatory signaling by Kupffer cells contributes to alcoholic liver disease (ALD). Here we investigated the impact of small-specific sized hyaluronic acid of ~35kD (HA35) on ethanol-induced sensitization of Kupffer cells, as well as ethanol-induced liver injury in mice. Un-biased analys...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Saikia, Paramananda, Bellos, Damien, McMullen, Megan R., Pollard, Katherine A., de la Motte, Carol, Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519440/
https://ncbi.nlm.nih.gov/pubmed/28257601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29144
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