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Specifically-sized hyaluronan (35 kDa) prevents ethanol-induced disruption of epithelial tight junctions through a Layilin-dependent mechanism in Caco-2 cells

BACKGROUND: Specific-sized species of the carbohydrate hyaluronan elicit a variety of cellular responses mediating tissue integrity and repair, as well as regulating inflammatory responses. Orally provided hyaluronan with an average molecular weight of 35kDa (HA35) protects mice from short term etha...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Bellos, Damien A., Sharma, Dhara, McMullen, Megan R., Wat, Jeanette, Saikia, Paramananda, de la Motte, Carol A., Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721967/
https://ncbi.nlm.nih.gov/pubmed/31237689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14140
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