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Adiponectin normalizes LPS-stimulated TNF-α production by rat Kupffer cells after chronic ethanol feeding

Chronic ethanol feeding sensitizes Kupffer cells to activation by lipopolysac-charide (LPS), leading to increased production of tumor necrosis factor-α (TNF-α). Adiponectin treatment protects mice from ethanol-induced liver injury. Because adiponectin has anti-inflammatory effects on macrophages, we...

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Detalhes bibliográficos
Main Authors: Thakur, Varsha, Pritchard, Michele T., McMullen, Megan R., Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975781/
https://ncbi.nlm.nih.gov/pubmed/16410364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00553.2005
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