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Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos
Aneuploidy, the inheritance of an atypical chromosome complement, is common in early human development and is the primary cause of pregnancy loss. By screening day-3 embryos during in vitro fertilization cycles, we identified an association between aneuploidy of putative mitotic origin and linked ge...
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| 發表在: | Science |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519344/ https://ncbi.nlm.nih.gov/pubmed/25859044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa3337 |
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