Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos

Aneuploidy, the inheritance of an atypical chromosome complement, is common in early human development and is the primary cause of pregnancy loss. By screening day-3 embryos during in vitro fertilization cycles, we identified an association between aneuploidy of putative mitotic origin and linked ge...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Science
Autori principali: McCoy, Rajiv C., Demko, Zachary, Ryan, Allison, Banjevic, Milena, Hill, Matthew, Sigurjonsson, Styrmir, Rabinowitz, Matthew, Fraser, Hunter B., Petrov, Dmitri A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519344/
https://ncbi.nlm.nih.gov/pubmed/25859044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa3337
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi