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Intravascular AAV9 administration for delivering RNA silencing constructs to the CNS and periphery
Viral vector delivery of RNA silencing constructs, when administered into vasculature, typically results in poor central nervous system (CNS) transduction due to the inability of the vector to cross the blood-brain-barrier (BBB). However, adeno-associated virus serotype 9 (AAV9) has the ability to c...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519340/ https://ncbi.nlm.nih.gov/pubmed/26472457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3112-5_21 |
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