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Osr1 functions downstream of Hedgehog pathway to regulate foregut development

During early fetal development, paracrine Hedgehog (HH) ligands secreted from the foregut epithelium activate Gli transcription factors in the surrounding mesenchyme to coordinate formation of the respiratory system, digestive track and the cardiovascular network. Although disruptions to this proces...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Han, Lu, Xu, Jingyue, Grigg, Emily, Slack, Megan, Chaturvedi, Praneet, Jiang, Rulang, Zorn, Aaron M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519324/
https://ncbi.nlm.nih.gov/pubmed/28501478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.05.005
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