A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin.

To kill human or primate cells expressing the p55 subunit of the interleukin 2 receptor, we have constructed a single-chain immunotoxin. DNA sequences encoding the first 388 amino acids of diphtheria toxin (DT) were fused to DNA elements encoding the antigen-binding portion (variable region or Fv) o...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chaudhary, V K, Gallo, M G, FitzGerald, D J, Pastan, I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9491
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!