A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling

Here, by combining lipidomics with transcriptome analysis, we demonstrate that Rb depletion in mouse embryonic fibroblastss induces significant alterations in their lipid composition. We discovered that Rb depletion induced increase in lysophosphatidylserine, diacylglycerol (DAG), fatty acid (FA), a...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Muranaka, H, Hayashi, A, Minami, K, Kitajima, S, Kohno, S, Nishimoto, Y, Nagatani, N, Suzuki, M, Kulathunga, L A N, Sasaki, N, Okada, N, Matsuzaka, T, Shimano, H, Tada, H, Takahashi, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519198/
https://ncbi.nlm.nih.gov/pubmed/28650445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.51
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